A simpler sort of antibody.

A simpler sort of antibody.

The monoclonal antibody NEMO is directed against a molecule expressed by human cells of the melanocytic lineage. Although obtained by conventional immunization and fusion procedures, NEMO consists solely of kappa light chain. SDS/PAGE analysis indicates that the kappa chains are present as both monomers and dimers. When these two forms were separated by gel filtration, only the monomeric form b...

A Simpler Minimum Spanning

The problem considered here is that of determining whether a given spanning tree is a minimal spanning tree. In 1984, Komll os presented an algorithm which required only a linear number of comparisons, but nonlinear overhead to determine which comparisons to make. We simplify his algorithm and give a linear time procedure for its implementation in the unit cost RAM model. The procedure uses tab...

A Simpler Approach Toweighted

In this paper, we analyze the performance of weighted 1 minimization over a non-uniform sparse signal model by extending the “Gaussian width” analysis proposed in [1]. Our results are consistent with those of [7] which are currently the best known ones. However, our methods are less computationally intensive and can be easily extended to signals which have more than two sparsity classes. Finall...

A simpler twist of fate.

Until the day it dies, a cell that has become a skin cell remains a skin cell — or so scientists used to think. Over the past decade, it has become clear that cellular identity is not written in stone but can be rewritten by activating specific genetic programs. Today, the field of regenerative medicine faces a question: should this rewriting take the conventional route, in which mature cells a...

A Simpler Origin of Life